Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| BRCA | rs9480928 | chr6:97211616 | C/G | 1.49E-7 | 1028 | 21.62 | 21.5 | 12.12 | KM Plot |
| BRCA | rs9490396 | chr6:122382588 | A/G | 2.84E-6 | 1028 | 14.35 | 29.67 | 21.02 | KM Plot |
| BRCA | rs9882616 | chr3:46317551 | A/T | 3.21E-6 | 1028 | 22.03 | 18.4 | 20.4 | KM Plot |
| CESC | rs10435420 | chr7:135208500 | T/C | 6.9E-5 | 216 | 17.07 | 13.22 | 12.83 | KM Plot |
| CESC | rs10812524 | chr9:27075026 | T/A | 2.76E-10 | 219 | 15.2 | 11.63 | 0.87 | KM Plot |
| CESC | rs10877094 | chr12:58697740 | T/C | 1.66E-5 | 212 | 13.12 | 17.27 | 2.47 | KM Plot |
| CESC | rs10967710 | chr9:27097498 | A/C | 1.25E-9 | 219 | 15.13 | 11.83 | 0.83 | KM Plot |
| CESC | rs10967711 | chr9:27099775 | A/G | 1.36E-9 | 218 | 15.13 | 11.63 | 0.83 | KM Plot |
| CESC | rs11038465 | chr11:45455522 | A/C | 3.28E-7 | 224 | 14.7 | 10.47 | 5.53 | KM Plot |
| CESC | rs11067659 | chr12:110083078 | T/C | 0 | 216 | 14.48 | 14.7 | 1.13 | KM Plot |
| CESC | rs11089620 | chr22:21922456 | C/G | 5.62E-5 | 222 | 15.7 | 13.77 | 7.57 | KM Plot |
| CESC | rs11167515 | chr5:150239471 | G/T | 9.82E-6 | 221 | 14.8 | 9.57 | 12.05 | KM Plot |
| CESC | rs11172530 | chr12:58694831 | G/A | 0.000101 | 214 | 13 | 17.27 | 3.2 | KM Plot |
| CESC | rs112575251 | chr16:1867370 | C/A | 4.58E-5 | 224 | 13.8 | 15.17 | 6.02 | KM Plot |
| CESC | rs11650923 | chr17:29008167 | G/A | 0 | 220 | 14.18 | 9.83 | 1.23 | KM Plot |